Dr Opoku-Mensah is currently working for the United Nations Economic Commission for Africa (ECA) in Addis Ababa, Ethiopia as Special Advisor to the ECA Executive Secretary on Special Initiatives & SDGs/Agenda 2030, and her responsibilities includes the coordination of activities at the continental and global levels, working with key partners. She also has special responsibilities for coordinating activities on Illicit Financial Flows (IFF) and managing the High Level Panel on Migration in ECA. Her previous roles in the same organization were as Director, ICT, Science & Technology Division, where she managed ECA’s programme on Harnessing Information, Science and Technology for Africa’s Development, which included the Knowledge, Library and Information Services programme. As Director of that division, she specifically led and implemented impressive initiatives such as UNECA’s African Information Society Initiative (AISI) a continental digital agenda supporting African countries to develop and implement national ICT4D policies and strategies, Technology in Government in Africa Awards (TIGA) to encourage African Governments’ use of technology for development, and was one of the co-architects of the Innovation Prize for Africa (IPA) – an initiative to encourage African innovators and inventors to enhance their roles in the African development process.